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KMID : 0604520140400010021
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Journal of the Society of Cosmetic Scientists of Korea
2014 Volume.40 No. 1 p.21 ~ p.28
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Effects of Eucommia ulmoides Oliver Extract on Inhibition of β-hexosaminidase and Keratinocyte Differentiation
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Hong In-Kee
Kim Eun-Ji
Seok Ji-Hyun
Kim Bo-Hyeon
Jang Jin-Dong
Joe Gi-Jung
Choi Shin-Wook
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Abstract
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In this study, Eucommia ulmoides Oliver extracts was studied in order to see any effects on the β-hexosaminidaserelease suppression of RBL-2H3 cells and on the expression of filaggrin, transglutaminase-1 (TGase-1) andcornified cell envelope (CE) related to the recovery of HaCaT keratinocyte skin barrier. Results showed that Eucommiaulmoides Oliver extracts reduced β-hexosaminidase release in RBL-2H3 cells and increased the effects of Eucommiaulmoides Oliver extract on the expression of filaggrin, transglutaminase-1 (TGase-1) and cornified cell envelope (CE)in HaCaT keratinocytes. Taken together, these results suggested that Eucommia ulmoides Oliver extract may be applicablefor keratinocyte differentiation.
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KEYWORD
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Eucommia ulmoides Oliver, anti-allergic, skin barrier, filaggrin, cornifide envelope
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